Conducta médica en la prueba de puente del miocardio - Revisión de la literatura.

MARQUES, João Rodrigues Cordeiro; BICHOFE  Remes Anderson; KAISER, Karynn Teixeira; LUNARDI, Jennifer Cadoná; SOUZA, Marcos Flávio; CABALLERO,  Gabi Roseli Peralta; FRANCO, Solanche Molinas; SANGALETTE, Beatriz Sobrinho; TOLEDO, Gustavo Gustavo; VIOLATO, João Pedro Felicio; MARQUES, João Rodrigues Cordeiro; LUNARDI, Jennifer Cadoná; BUENO, Mariellen Nayara De Almeida; SA, Kim Fonseca Gomes; SOUZA,  Flávio Marcos; MARQUES, João Rodrigues Cordeiro; INÁCIO, Rodrigo Fabrizzio INÁCIO, Rodrigo Fabrizzio; PERPETUO, Fabio Luis PERPETUO, Fabio Luis; REGO, Antonine de Amorim REGO, Antonine de Amorim

Autores/as

INÁCIO, Rodrigo Fabrizzio UNIVERSIDAD CENTRAL DEL PARAGUAY https://orcid.org/0000-0003-1464-0466
PERPETUO, Fabio Luis UNIVERSIDAD CENTRAL DEL PARAGUAY https://orcid.org/0000-0002-6405-9226
REGO, Antonine de Amorim UNIVERSIDAD CENTRAL DEL PARAGUAY https://orcid.org/0000-0001-5432-6717

Palabras clave:

Insulina, Resistencia a Insulina, Diagnóstico Diferencial, Experiencia Clínica, Alteración Metabólica

Resumen

La resistencia a la insulina se puede definir como una respuesta disminuida a las acciones biológicas de la misma, una anomalía que ocurre principalmente debido a la acción inadecuada de la insulina en los tejidos periféricos, como el tejido adiposo, muscular y hepático. Varias condiciones clínicas, como la obesidad, la diabetes mellitus, la hipertensión, los procesos infecciosos y las enfermedades endócrinas se correlacionan con la resistencia a la insulina. La relación entre las partículas proaterogénicos (que contienen ApoB) y las partículas antiaterogénicas (que contienen ApoA1) puede estar asociada con componentes del síndrome metabólico, como el aumento de la circunferencia de la cintura y la presión arterial, el bajo nivel de HDL-c y los triglicéridos altos, además de ser un posible predictor cardiometabólico para la aterosclerosis.
Este trabajo tiene como objetivo evaluar 2 casos clínicos, teniendo los parámetros realizados por análisis de laboratorio. La evaluación fue dada específicamente al estado clínico de los pacientes, apoyando la proporción de ApoA1 y ApoB, dándoles índices de HDL y LDL, así como la alteración metabólica o resistencia a la insulina.
Como resultado, teniendo en cuenta el índice de normalidad (≤ 0,75), se aplicó la relación ApoB / ApoA1 a ambos pacientes. Los resultados condujeron a una nota de normalidad para el paciente 1 y una alteración para el paciente 2, es decir, presentando resistencia a la insulina. Este trabajo pretende colaborar con la exploración científica en los exámenes de laboratorio, aportando a la experiencia clínica un mejor enfoque terapéutico para el paciente con resistencia a la insulina.

Biografía del autor/a

INÁCIO, Rodrigo Fabrizzio, UNIVERSIDAD CENTRAL DEL PARAGUAY

Académico del 7to período de Medicina, Mestre y doctor en Ortopedia y Traumatología, Biología Celular y Estructural, Investigador y Colaborador del Núcleo de Investigación UCP.

PERPETUO, Fabio Luis, UNIVERSIDAD CENTRAL DEL PARAGUAY

Académico del 7to período de Medicina, Especialista en Ortopedia y traumatología, Investigador y Colaborador del Núcleo de Investigación UCP

REGO, Antonine de Amorim, UNIVERSIDAD CENTRAL DEL PARAGUAY

Académico del 7to período de Medicina, Colaborador del Núcleo de Investigación de la Universidad Central del Paraguay

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