Conducta médica en la prueba de puente del miocardio - Revisión de la literatura.

MARQUES, João Rodrigues Cordeiro; BICHOFE  Remes Anderson; KAISER, Karynn Teixeira; LUNARDI, Jennifer Cadoná; SOUZA, Marcos Flávio; CABALLERO,  Gabi Roseli Peralta; FRANCO, Solanche Molinas; SANGALETTE, Beatriz Sobrinho; TOLEDO, Gustavo Gustavo; VIOLATO, João Pedro Felicio; MARQUES, João Rodrigues Cordeiro; LUNARDI, Jennifer Cadoná; BUENO, Mariellen Nayara De Almeida; SA, Kim Fonseca Gomes; SOUZA,  Flávio Marcos; MARQUES, João Rodrigues Cordeiro; INÁCIO, Rodrigo Fabrizzio INÁCIO, Rodrigo Fabrizzio; PERPETUO, Fabio Luis PERPETUO, Fabio Luis; REGO, Antonine de Amorim REGO, Antonine de Amorim

Authors

INÁCIO, Rodrigo Fabrizzio CENTRAL UNIVERSITY OF PARAGUAY https://orcid.org/0000-0003-1464-0466
PERPETUO, Fabio Luis CENTRAL UNIVERSITY OF PARAGUAY https://orcid.org/0000-0002-6405-9226
REGO, Antonine de Amorim CENTRAL UNIVERSITY OF PARAGUAY https://orcid.org/0000-0001-5432-6717

Keywords:

Insulin, Insulin resistance, Differential diagnosis, Clinical experience, Metabolic alteration

Abstract

Insulin resistance can be defined as a diminished response to the biological actions of insulin, an abnormality that occurs primarily due to inadequate action of insulin on peripheral tissues such as adipose, muscle, and liver tissue. Several clinical conditions, such as obesity, diabetes mellitus, hypertension, infectious processes, and endocrine diseases are correlated with insulin resistance.
The relationship between pro-atherogenic particles (containing ApoB) and anti-atherogenic particles (containing ApoA1) may be associated with components of the metabolic syndrome, such as increased waist circumference and blood pressure, low HDL -c and high triglycerides, in addition to being a possible cardiometabolic predictor for atherosclerosis.
This work aims to evaluate 2 clinical cases, having the parameters performed by laboratory analysis. The evaluation was given specifically to the clinical status of the patients, supporting the ratio of ApoA1 and ApoB, giving them HDL and LDL indices, as well as metabolic alteration or insulin resistance. As a result, taking into account the normality index (≤ 0.75), the ApoB / ApoA1 ratio was applied to both patients.
The results led to a note of normality for patient 1 and an alteration for patient 2, that is, presenting insulin resistance. This work aims to collaborate with scientific exploration in laboratory tests, contributing to clinical experience a better therapeutic approach for patients with insulin resistance.

Author Biographies

INÁCIO, Rodrigo Fabrizzio, CENTRAL UNIVERSITY OF PARAGUAY

Academic of the 7th period of Medicine, Mestre and doctor in Orthopedics and Traumatology, Cellular and Structural Biology, Researcher and Collaborator of the UCP Research Center.

PERPETUO, Fabio Luis, CENTRAL UNIVERSITY OF PARAGUAY

Academic of the 7th period of Medicine, Specialist in Orthopedics and Traumatology, Researcher and Collaborator of the UCP Research Center

REGO, Antonine de Amorim, CENTRAL UNIVERSITY OF PARAGUAY

Academic of the 7th period of Medicine, Collaborator of the Research Center of the Central University of Paraguay

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